Fig. 3

CircRNA circPPP1R12A promotes the cell proliferation, but not migration and invasion abilities of CC cells. a Schematic illustration and real-time PCR confirmation showing circPPP1R12A overexpression in DLD-1 and Caco-2 cells. b CircPPP1R12A promoted the proliferation of DLD-1 and Caco-2 cells shown by CCK8 assay. c CircPPP1R12A promoted the proliferation of DLD-1 and Caco-2 cells shown by colony formation assay. d CircPPP1R12A did not affect the migration of DLD-1 and Caco-2 cells shown by wound healing assay. e CircPPP1R12A did not affect the invasion of DLD-1 and Caco-2 cells shown by matrigel assay. The data are represented as the means ± SEM; *P < 0.05